ÚJV Řež also deals with the back-end part of the fuel cycle of nuclear power plants and research reactors. These activities include preparation of the closure of the reactor fuel cycle and the elaboration of conceptual and expert studies to optimize spent fuel management in the European context of fissile materials management. See more: Radioactive waste and decommisioning.

ÚJV Řež is also engaged in the study and modeling of phenomena that can endanger the integrity of the fuel rods cladding and the preparation of fuel pellet temperature models under operational conditions. ABAQUS software is used for these tasks.